Damon Wayans reunites with David Alan Grier on NBC's *St. Denis Medical*

Damon Wayans will return to TV comedy in NBC’s mockumentary *St. Denis Medical*, landing a guest role as Dr. Highland after producers reached out to reunite him with David Alan Grier.

The casting comes more than 30 years after the pair first teamed up on *In Living Color*, the sketch show that launched both comedians into stardom. Wayans played multiple characters on the Fox series, while Grier became a standout as the show’s musical and comedic anchor. Their chemistry helped define *In Living Color*’s golden era in the early 1990s, making their reunion a nostalgic draw for fans.

NBC announced the casting on Monday, but didn’t reveal which episode Wayans will appear in. Grier, who stars as Dr. Leo Mays in the series, has previously joked about wanting to bring back old *In Living Color* castmates. Wayans, 59, has kept a lower TV profile in recent years after starring in his own sitcoms and appearing in films like *Major Payne*. His return marks a shift back toward scripted TV after years focused on stand-up and producing.

Reuniting Wayans and Grier could boost ratings for *St. Denis Medical*, which has struggled to find a consistent audience since its 2023 debut. The series is a medical satire set in a struggling hospital, led by Grier and co-star Brian Benben. Wayans’ involvement suggests the show might lean into the nostalgia of its cast, drawing comparisons to other revived ensembles like *Ghosts* on CBS. Whether this leads to a recurring role or just a one-off cameo remains unclear. But for fans of ’90s comedy, it’s a welcome callback to a time when Wayans and Grier ruled the small screen.